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Acromegaly: Symptoms


Symptoms of Acromegaly:

Soft tissue thickening (flesh) palms of hands and soles of feet

Oily skin

Coarse facial features

Excessive sweating

Low vitality (fatigue)


Carpal tunnel syndrome

Enlarging jaw (under bite)

Spreading teeth (food gets caught)

Change or loss of normal menstrual function


Mood disorders


Potency decrease


Loss of sexual interest (libido)

Enlarging hands (ring size)

Enlarging feet (shoe size)

Enlarging head (hat size)


Sleep apnea

Vision defects (peripheral)

Multiple skin tags

Milk discharge from nipples


At risk for colon polyps


Acromegaly Symptoms:

enlarged hands

enlarged feet

widened fingers or toes due to skin overgrowth with swelling, redness, and pain.

enlarged jaw (prognathism)

enlarged facial bones

thickening of the skin

enlarged sebaceous glands



double vision


easy fatigue

excessive sweating

decreased muscle strength (weakness)

motion limitation, or loss of range of motion

joint pain (hip pain, knee pain, ankle pain, foot pain, pain over the small joints of the foot, shoulder pain, elbow pain, wrist pain, hand pain, pain over the small joints of the hand, or pain in any other joint)

carpal tunnel syndrome

change in face appearance, developed over less than 1 year

widely spaced teeth

swelling of the bony areas around a joint

In infants anterior fontanel can remain open for years.

Additional symptoms that may be associated with this disease:

weight gain (unintentional)

tongue problems

skin, abnormally dark or light

hair, excessive on females

Signs and tests:

The level of growth hormone is abnormal.

A spine x-ray shows periosteal bone growth.

A cranial MRI or cranial CT scan is abnormal and may show pituitary tumor.

This disease may also alter the results of the following tests:

glucose test


creatinine - urine



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