“Subclinical Cushing’s syndrome” is not subclinical: improvement after adrenalectomy in 9 patients
“Subclinical Cushing’s syndrome” is not subclinical: improvement after adrenalectomy in 9 patients
Overall, 24 patients underwent adrenalectomy for adrenal cortisol hypersecretion, of which 9 were found to have subclinical Cushing's Syndrome. Median serum cortisol was 2.0 ?g/dL (range, 1.1–6.1) after 1-mg overnight dexamethasone suppression testing. Suspicious clinical findings on preoperative examination included skin bruising, unexplained weight gain, proximal muscle weakness, abnormal fat pads, skin thinning, fatigue, and facial plethora. During a median follow-up period of 5 months (range, 1–30 months), all 8 patients with easy bruising noted resolution postoperatively. Fatigue improved in 4 of 5 patients, muscle weakness in 6 of 8 patients, and weight in 7 of 9 patients, with a median body mass index change of –2.0 kg/m2 (range, –7.1 to +0.5 kg/m2)...
This Topic on the Message Boards
American Association of Endocrine Surgeons
Overall, 24 patients underwent adrenalectomy for adrenal cortisol hypersecretion, of which 9 were found to have subclinical Cushing's Syndrome. Median serum cortisol was 2.0 ?g/dL (range, 1.1–6.1) after 1-mg overnight dexamethasone suppression testing. Suspicious clinical findings on preoperative examination included skin bruising, unexplained weight gain, proximal muscle weakness, abnormal fat pads, skin thinning, fatigue, and facial plethora. During a median follow-up period of 5 months (range, 1–30 months), all 8 patients with easy bruising noted resolution postoperatively. Fatigue improved in 4 of 5 patients, muscle weakness in 6 of 8 patients, and weight in 7 of 9 patients, with a median body mass index change of –2.0 kg/m2 (range, –7.1 to +0.5 kg/m2)...
This Topic on the Message BoardsAmerican Association of Endocrine Surgeons
Labels: news
posted by MaryO at
11:06 AM
0 Comments:
Post a Comment
<< Home